Rejuran Skin Boosters | PN & PDRN

What Are PN & PDRN?

The Science Behind the Salmon Sperm Skincare Trend.

Yes, the buzz about salmon sperm skincare is real—but the science is much more sophisticated than the nickname suggests.

PN and PDRN are purified DNA-derived ingredients, often sourced from salmon or trout reproductive cells and processed for use in specialized aesthetic formulations.

Both have attracted attention for their potential roles in skin health, but there's an important distinction.

PN | Polynucleotides

Longer DNA Chains. Skin Quality & Structural Support.

PN generally consists of longer-chain DNA polymers with a higher molecular weight.

In aesthetic medicine, PN is being studied for its potential to support skin hydration, elasticity, texture, and extracellular matrix remodeling.

PN-based formulations are especially interesting for patients concerned about skin that appears thin, crepey, dehydrated, or less supple.

PDRN | Polydeoxyribonucleotides

Shorter DNA Fragments. Cellular Signaling & Repair Research.

PDRN generally consists of shorter DNA fragments that are being studied for their involvement in cellular signaling, nucleotide recycling, and tissue-repair pathways.

In skin-quality treatments, PDRN is often combined with ingredients such as hyaluronic acid, amino acids, antioxidants, and brightening complexes.

The difference? PN is generally associated with longer DNA chains and their structural properties, while PDRN is associated with shorter fragments and biological signaling pathways. Both are being explored in regenerative skin health, although their effects depend on the specific formulation and delivery method.

Discover the Rejuran Collection at Pure Skin Palm Beach

Four Formulations. Four Skin Health Goals.

We've selected four Rejuran boosters that allow us to personalize treatments for hydration, luminosity, delicate under-eye skin, and overall skin quality.

Rejuran Healing Essence | 2% PN

Repair. Renew. Rejuvenate.

Our advanced 2% PN formulation features hydrolyzed DNA and mannitol, with DOT™ technology.

Designed for patients seeking a more focused approach to overall skin quality, Rejuran Healing Essence is selected for concerns involving uneven texture, dehydration, and loss of suppleness.

Ideal treatment focus: Skin texture, hydration, elasticity, and a smoother, refreshed-looking complexion.

Rejuran I Booster | 2% PN

Targeted Under-Eye Skin Rejuvenation.

The delicate skin around our eyes is often one of the first areas to reveal changes in hydration, texture, and elasticity.

Our Rejuran I Booster features 2% PN and is selected for targeted eye-area treatments, with an emphasis on improving the appearance of crepey texture, fine lines, and tired-looking under-eye skin.

This specialized treatment can be incorporated into a personalized eye rejuvenation Plan of Care.

Ideal treatment focus: Under-eye skin quality, fine lines, crepey texture, and hydration.

Rejuran Tone Up Booster | 1% PDRN

Brighten. Illuminate. Even Tone.

For skin that appears dull, uneven, or affected by visible discoloration, Rejuran Tone Up combines 1% PDRN with a targeted brightening complex.

Key ingredients include:

• Glutathione — antioxidant support

• Vitamin C — brightening and antioxidant care

• Tranexamic Acid — an ingredient used in tone-focused skincare formulations

Together, these ingredients are selected to support a brighter, more luminous, even-looking complexion.

Ideal treatment focus: Dullness, uneven-looking tone, and overall radiance.

Rejuran HA Booster | 1% PDRN

Hydrate. Replenish. Restore Your Glow.

Hydration is one of the foundations of beautiful skin.

Our Rejuran HA Booster combines 1% PDRN with hyaluronic acid and amino acids for a moisture-focused skin-conditioning treatment.

Hyaluronic acid helps attract and retain moisture, while selected amino acids complement the formulation's skin-conditioning properties.

Ideal treatment focus: Dehydrated skin, dullness, rough-looking texture, and a supple, dewy complexion.

Which Rejuran Booster Is Right for You?

Whether your goal is improving the appearance of fine lines around the eyes, restoring a more hydrated complexion, refining texture, or brightening uneven-looking skin, our skin health specialists will help determine the most appropriate Rejuran formulation.

Treatments may be enjoyed individually or incorporated into a long-term skin health Plan of Care alongside other aesthetic services.

Because beautiful skin isn't just about what we see on the surface. It's about understanding the science behind skin quality.

Experience Rejuran at Pure Skin Palm Beach.

Korean innovation. Salmon DNA science. Personalized skin rejuvenation.

Discover how our Rejuran Skin Booster Collection can complement your journey toward smoother, more radiant, healthier-looking skin.